Rate of Occult Cervical Lymph Node Involvement in Supraglottic Squamous Cell Carcinoma

نویسندگان

  • Amin Amali Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, Iran
  • Behrooz Amirzargar Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, Iran
  • Fatemeh Tavakolnejad Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, Iran
  • Mehrdad Jafari Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, Iran
  • Mohammad Sadeghi Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, Iran
چکیده مقاله:

Introduction: To assess the rate of cervical lymph node involvement in patients with supraglottic squamous cell carcinoma (SCC) with no lymph node in clinical assessments and radiological studies. Materials and Methods: Fifty-six patients who underwent elective dissection of the cervical lymph node of the second through fourth level were enrolled, and pathologic evaluation of the dissected lymph nodes was performed. Lymph node involvement and association between tumor grade, smoking and gender with lymph node involvement were assessed. Results: The rate of the occult neck metastasis in this series was 37.5%. There was no statistically significant association between lymph node involvement and tumor grade, smoking, or gender. Conclusion: Based on the results of our study, we recommend elective bilateral neck dissection in all stages of N0 supraglottic SCC patients.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Prediction of occult cervical lymph node metastasis in clinically negative supraglottic squamous cell carcinoma

For citation purposes: Zeng R, Dai Q, Peng Z, Cai P, Hu W. Prediction of occult cervical lymph node metastasis in clinically negative supraglottic squamous cell carcinoma. Head Neck Oncol. 2012 Oct 27;4(3):69. Licensee OA Publishing London 2012. Creative Commons Attribution License (CC-BY) Abstract Objective Supraglottic laryngeal carcinomas are often accompanied by occult cervical lymph node m...

متن کامل

DETERMINATION OF THE PREVALENCE OF OCCULT NECK LYMPH NODE INVOLVEMENT IN PATIENTS WITH LARYNGEAL SQUAMOUS CELL CARCINOMA

Background & Aims: Squamous cell carcinoma (SCC) accounts for 85% of laryngeal cancers. In some cases, lymph nodes do not show any specific symptoms despite being involved by cancer. Previous studies showed that patients undergoing selective neck lymph node dissection (SND) had significantly lower recurrence rates. We investigated the prevalence of occult neck lymph node involvement in patients...

متن کامل

Correlation between p33ING1b Cytoplasmic Transfer and Lymph Node Metastasis in Oral Squamous Cell Carcinoma

Background: Oral squamous cell carcinoma is the sixth most common malignancy in the world today.  ING1b/p33 is a newly-discovered tumor suppressor which enhances p53 activity. Transfer of p33 protein from nucleus to cytoplasmic compartment has been previously reported in leukemias. The objective of this study was to determine the correlation between p33ing1b cytoplasmic transfer and lymph node ...

متن کامل

Clinicopatholgic Parameters Associated With Regional Lymph Node Metastasis In Oral Squamous Cell Carcinoma: A Retrospective Study

  Background and Objective: Oral cancer accounts for less than 3% of all cancers. Despite recent improvement in diagnostic and treatment methods, the overall survival of the disease is unfavorable. Several studies have been performed to assess factors influencing lymph node metastasis and prognosis. The aim of this study was to evaluate some clinical and pathological factors influencing lymph ...

متن کامل

interleukin-4 mrna expression in laryngeal squamous cell carcinoma patients with or without lymph node involvement

background : interleukin (il)-4 is a member of t helper 2 (th2) axis produced by t-lymphocyte and mast cell. it has been shown that il-4 expression changes in tumor tissues. the main objective of this study is to investigate the expression of il-4 mrna in patients with laryngeal squamous cell carcinoma (lscc) with or without lymph node involvement. materials and methods: mrna expression of il-4...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


عنوان ژورنال

دوره 29  شماره 3

صفحات  133- 136

تاریخ انتشار 2017-05-01

با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023